I was trying to track down an exception that was bubbling to the top of the stack. I went intoDebug->Exceptions options and set all exception types to be caught when they are thrown (not just when they are unhandled). To my surprise, there are a great deal of exceptions thrown while the view (WorkflowView) is being created and added to the form. All of these exceptions are are handled, so we would not normally see them if debugging options aren't changed. Still, throwing this many exceptions has to adversely affect performance. Please check into this when possible. Here's an exception trace:

Exception
{"Could not find any resources appropriate for the specified culture or the neutral culture. Make sure \"System.Workflow.Activities.resources\" was correctly embedded or linked into assembly \"System.Workflow.Activities\" at compile time, or that all the satellite assemblies required are loadable and fully signed."} System.Exception {System.Resources.MissingManifestResourceException}

Stack
mscorlib.dll!System.Resources.ResourceManager.InternalGetResourceSet(System.Globalization.CultureInfo culture = {Dimensions:[2]}, bool createIfNotExists = true, bool tryParents = true) + 0x4f9 bytes
mscorlib.dll!System.Resources.ResourceManager.InternalGetResourceSet(System.Globalization.CultureInfo culture = {en}, bool createIfNotExists, bool tryParents) + 0x513 bytes
mscorlib.dll!System.Resources.ResourceManager.InternalGetResourceSet(System.Globalization.CultureInfo culture = {en-US}, bool createIfNotExists, bool tryParents) + 0x513 bytes
mscorlib.dll!System.Resources.ResourceManager.GetObject(string name = "SequentialWorkflowDesigner", System.Globalization.CultureInfo culture = {en-US}, bool wrapUnmanagedMemStream = true) + 0x6a bytes
mscorlib.dll!System.Resources.ResourceManager.GetObject(string name) + 0x9 bytes
System.Workflow.ComponentModel.dll!System.Workflow.ComponentModel.Design.DesignerHelpers.GetImageFromPath(System.Workflow.ComponentModel.Design.DesignerTheme designerTheme, string directory, string path) + 0x18c bytes
System.Workflow.ComponentModel.dll!System.Workflow.ComponentModel.Design.CompositeDesignerTheme.WatermarkImage.get() + 0x33 bytes
System.Workflow.ComponentModel.dll!System.Workflow.ComponentModel.Design.WorkflowRootDesigner.UpdatePageStripSize() + 0xd5 bytes
System.Workflow.ComponentModel.dll!System.Workflow.ComponentModel.Design.WorkflowRootDesigner.Size.set(System.Drawing.Size value) + 0x23 bytes
System.Workflow.ComponentModel.dll!System.Workflow.ComponentModel.Design.WorkflowRootDesigner.OnLayoutSize(System.Workflow.ComponentModel.Design.ActivityDesignerLayoutEventArgs e = {System.Workflow.ComponentModel.Design.ActivityDesignerLayoutEventArgs}) + 0xbe bytes
System.Workflow.ComponentModel.dll!System.Workflow.ComponentModel.Design.ActivityDesigner.System.Workflow.ComponentModel.Design.IWorkflowDesignerMessageSink.OnLayoutSize(System.Drawing.Graphics graphics) + 0x5c bytes
System.Workflow.ComponentModel.dll!System.Workflow.ComponentModel.Design.WindowManager.OnLayout(System.Windows.Forms.LayoutEventArgs eventArgs) + 0x48 bytes
System.Workflow.ComponentModel.dll!System.Workflow.ComponentModel.Design.WorkflowDesignerMessageFilter.System.Workflow.ComponentModel.Design.IWorkflowDesignerMessageSink.OnLayout(System.Windows.Forms.LayoutEventArgs layoutEventArgs) + 0x8 bytes
System.Workflow.ComponentModel.dll!System.Workflow.ComponentModel.Design.WorkflowView.OnLayout(System.Windows.Forms.LayoutEventArgs levent = {System.Windows.Forms.LayoutEventArgs}) + 0x3db bytes
System.Windows.Forms.dll!System.Windows.Forms.Control.PerformLayout(System.Windows.Forms.LayoutEventArgs args) + 0x69 bytes
System.Windows.Forms.dll!System.Windows.Forms.Control.PerformLayout() + 0x13 bytes
System.Windows.Forms.dll!System.Windows.Forms.Control.ResumeLayout(bool performLayout = true) + 0x84 bytes
System.Workflow.ComponentModel.dll!System.Workflow.ComponentModel.Design.WorkflowView.ShowToolContainer.set(bool value) + 0x464 bytes
System.Workflow.ComponentModel.dll!System.Workflow.ComponentModel.Design.ActivityDesigner.System.ComponentModel.Design.IRootDesigner.GetView(System.ComponentModel.Design.ViewTechnology technology) + 0x8e bytes
System.Design.dll!System.ComponentModel.Design.DesignSurface.View.get() + 0x17a bytes
> WorkflowWorkshop.EXE!WorkflowWorkshop.WorkflowEditor.RecreateView() Line 105 + 0x10 bytes C#
WorkflowWorkshop.EXE!WorkflowWorkshop.WorkflowEditor.ServiceProvider.set(System.IServiceProvider value = {System.ComponentModel.Design.ServiceContainer}) Line 348 + 0x7 bytes C#
WorkflowWorkshop.EXE!WorkflowWorkshop.MainUI.MainUI() Line 44 + 0x13 bytes C#
WorkflowWorkshop.EXE!WorkflowWorkshop.Program.Main() Line 16 + 0x13 bytes C#
[Native to Managed Transition]
[Managed to Native Transition]
mscorlib.dll!System.AppDomain.ExecuteAssembly(string assemblyFile, System.Security.Policy.Evidence assemblySecurity, string[] args) + 0x38 bytes
Microsoft.VisualStudio.HostingProcess.Utilities.dll!Microsoft.VisualStudio.HostingProcess.HostProc.RunUsersAssembly() + 0x1d bytes
mscorlib.dll!System.Threading.ThreadHelper.ThreadStart_Context(object state) + 0x3b bytes
mscorlib.dll!System.Threading.ExecutionContext.Run(System.Threading.ExecutionContext executionContext, System.Threading.ContextCallback callback, object state) + 0x7d bytes
mscorlib.dll!System.Threading.ThreadHelper.ThreadStart() + 0x40 bytes